Proto-oncogenes and tumor-suppressor genes

Describe the normal function of proto-oncogenes and tumor-suppressor genes within the cell
and explain what occurs when these genes mutate. Which category of genes do BRCA1 and
BRCA2 fall under, and how are mutations in these genes related to breast cancer?
2. Are most forms of breast cancers inherited? Identify and discuss other factors that increase
one’s risk of breast cancer.
3. Discuss the pros and cons of BRCA genetic testing. Would you recommend this test to
female family members, even if there is no history of breast cancer in your family? Your
opinion must be supported by your references.
4. Was Angelina’s decision for a double mastectomy too extreme? If one of your family
members finds out that she has an increased risk of breast cancer, what preventative and
treatment options would you recommend and why? Your opinion must be supported by your
references.

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